Cutaneous Lymphoma
Cutaneous lymphoma is a type of Non-Hodgkin’s lymphoma
involving the lymphocytes within the skin, specifically T-cells
and B-Cells. This is a rare type of Non-Hodgkin’s lymphoma
where the tumor growths are seen mostly as numerous lumps
beneath the skin’s surface and not in just a lymph
node.
The lumps formed beneath the skin cutaneous lymphoma are due to
a collection of the malignant cells in the skin. In an attempt
to purge the system of the mutated cells, the body pushes the
clustered malignant cells towards the surface of the skin. The
most common type of cutaneous lymphoma is the cutaneous T-cell
lymphoma.
The disease manifests itself in several stages:
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Pre-tumor stage –
the skin is presented with raised, red patches that appear on
the breasts or buttocks and somewhat mimics the appearance of
other skin conditions such as eczema or psoriasis.
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Plaque stage –
the patches are now irregularly shaped and can appear anywhere
in the body. Hair loss in the affected skin area is also noted,
and can be permanent if the condition is not
treated.
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Tumor stage –
the incidence of people progressing to this stag is quite
small. The plaques can now form lumps and even ulcerate. Lymph
nodes are also affected. The liver, lungs, and spleen is also
at risk of being affected by the cutaneous lymphoma, but the
cases are quite rare.
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Sezary syndrome –
this is when the malignancy has spread and covers a large skin
area. The malignant cells have also metastasized in the blood
stream. Some patients have no plaques or tumors, but the entire
integumentary system may be swollen, red and sore (l’homme
rouge). The skin can also manifest desquamation or peeling off
of skin.
Cutaneous lymphoma of T-cell origin is treated through a
specific or a combination of treatment modalities that can
range from topical or local to systemic. PUVA treatment is a
combination of psoralen and UVA. After taking psoralen, the
patient enters an enclosed room where rays of UVA is applied on
the skin. However, extra care must be given for it is known
that exposure to UV rays can predispose a person to skin
cancer. Radiation therapy and chemotherapy is also done to help
cure cutaneous lymphoma.
Cutaneous lymphoma can be hard to deal with for it can cause
some severe changes in your appearance. A support group can
help you combat the disease both in its physical and
psychological aspects. Talk to your friends and family during
hard times, and ask your doctor to refer you to a cancer
support group to help you understand and cope with the effects
of cutaneous lymphoma.
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